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“Very effective” modelna vaccine against coronavirus mutants: research

Los Angeles: A double dose of the Moderna Covid-19 vaccine is very effective against SARS-CoV-2 variants, but protection against delta infections declines over time, according to a study conducted in the United States.
At the time of the study, Omicron variants had not yet been detected in the Southern California region, researchers said.
A study published Wednesday in the British Medical Journal showed that the vaccine was effective against Covid-19 hospitalizations associated with delta variants.
However, the effectiveness of the vaccine against the variant declined moderately with increasing time after vaccination.
“This study confirmed efficacy against all mutants during the study period, but efficacy against delta infections was 94% in the first 2 months after vaccination to 80% after 6 months. It has dropped to. ” Katia Bruxvoort, from Kaiser Permanente, USA.
“Protection against hospitalization from delta mutations remained high with 98% efficacy,” said Bruxvoort, lead author of the study.
Beginning in March 2021, Kaiser Permanente of Southern California began sending positive SARS-CoV-2 specimens from both symptomatic and asymptomatic people to contract laboratories for whole-genome sequencing.
The study, funded by Moderna, included 8,153 people who were positive for SARS-CoV-2 and samples were collected from March 1, 2021 to July 27, 2021.
Among them, 91.3% were unvaccinated, 1.4% were vaccinated once with the Moderna Covid-19 vaccine, and 7.3% were vaccinated twice with the preventive drug.
Researchers compared those who tested positive with those who tested negative.
People who received the double-dose Moderna vaccine were strongly protected from Covid-19 hospitalization associated with the Delta variant, they said.
According to the researchers, there were no deaths from hospitalization among those who received the two-dose Moderna Covid-19 vaccine.
They said the vaccine efficacy of the two-dose Moderna Covid-19 vaccine against delta infection was 87.9% in people aged 18-64 years and 75.2% in people aged 65 and over.
“This study provides solid evidence of the effectiveness of double doses of the Moderna Covid-19 vaccine in the prevention of Covid-19 infection and hospitalization due to mutations containing Delta, but it also affects booster shots.” Said Hung Fu Tseng of Kaiser Permanente. Southern California Research and Evaluation Bureau.
“The finding that the Moderna Covid-19 vaccine’s vaccine efficacy against delta infections has been moderately reduced supports current booster dose recommendations,” added Tseng, lead author of the study.



“Very effective” modelna vaccine against coronavirus mutants: research

Source link “Very effective” modelna vaccine against coronavirus mutants: research

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