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Research claims that COVID-19 affects sperm production and may be low in number

SARS-CoV-2, the causative agent of COVID-19, has also been shown to be present in the male gonads.

COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears It is thought to be a respiratory disorder that affects the lungs and respiratory tract. However, in the past few months, researchers have discovered that the disease can affect multiple organs, including the kidneys, heart, and testicles, which can lead to organ damage, damage, and even death. did.

It has been suggested that men in particular are more susceptible to the disease. According to experts, this may be due to high levels of ACE2 in the blood and testes, high levels of testosterone, and the presence of a single X chromosome (compared to women with two X chromosomes). do it).

Currently, a new study conducted in China shows that SARS-CoV-2 can affect the process of spermatogenesis (spermatogenesis), leading to a decrease in sperm count.

Survey results are published in open access journals Clinical medicine It is published by Lancet..

Previous research

Several viral diseases are known to affect the male reproductive system. These include hepatitis C virus, human immunodeficiency virus (HIV), herpesvirus, eboravirus, and human papillomavirus. These viruses affect spermatogenesis, sperm count, hormone levels, and sperm motility.

Experts suggest that high body temperature during viremia (the presence of the virus in the blood) can cause the virus to cross the blood-testis barrier and leak into the male reproductive tract. However, researchers say the virus may not need to be in the male reproductive tract to cause damage.

SARS-CoV-2, causative agent COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears It has also been shown to be present in the male gonads. Much information is not yet available regarding the effects of the virus on the male reproductive tract.

Latest research

In the current study, scientists investigated two different cohorts. In the first cohort, autopsy samples were taken from six dead men. COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears Semen samples from 23 men recovering from illness. In the control group, 6 surgical samples were taken from men with prostate cancer and 22 semen samples were taken from healthy men.

All men in the test group are 18 years of age or older COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears Infectious diseases within the last 7 days, have not been treated for infertility, have children who are naturally pregnant, have no children due to confirmed fertility problems in their wives, affect sperm production process No history of possible illness.

Some of the survey results are shown below.

  • Interstitial edema was found in both the testes and epididymis of all men COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears ..
  • The spermatogenesis process was found to be affected in all subjects.
  • COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears The patient had high levels of T cells and macrophages in the testicular tissue.
  • IgG, a type of antibody produced later in the infection, was found in 6 autopsy samples.
  • Expression of ACE2 was found in testis cells.
  • Approximately 9 of the 23 semen samples collected COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears The patient’s sperm concentration was less than 15 x 106 / mL. Typical sperm counts range from 15 x 106 to 20 x 106 / mL. Again, all these men had previously had children and had never been treated for infertility.
  • Approximately 14 patients showed white blood cell counts above 1 x 106 / mL, showing leukocyte azoospermia characterized by high white blood cell counts in semen, resulting in sperm DNA damage.

For more information, see the article on reducing sperm count.

The Firstpost Health article was created by myUpchar.com, India’s first and largest resource for validated medical information. At myUpchar, researchers and journalists work with doctors to provide all the information about health.

Research claims that COVID-19 affects sperm production and may be low in number

Source link Research claims that COVID-19 affects sperm production and may be low in number

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