A study by Virginia Commonwealth University followed more than 1,700 patients for a median of 4 years, some of whom were followed for 10 years to assess the results.
The team found that patients with advanced fibrosis were more likely to die, especially after gastrointestinal bleeding or accumulation of fluid in the abdomen and progressive deterioration of brain function due to liver disease.
Results published in the New England Journal of Medicine confirmed that people with highly injured livers are at greatest risk of death.
“This is the first clear picture of the true outcome rate of patients with (non-alcoholic fatty liver disease),” said Arun Sanial, liver disease specialist at VCU Health.
“And this study provides teeth to recent American Diabetes Association guidelines and initiates screening for liver disease, making screening more mainstream,” he added.
Many people believe that only excessive alcohol intake causes liver disease. However, a quarter of adults worldwide suffer from non-alcoholic fatty liver disease. This is a condition in which excess fat accumulates in the liver and is more closely associated with obesity and diabetes than alcohol consumption. Most people are unaware that they have or are at high risk for non-alcoholic fatty liver disease.
If left untreated, the disease can progress to advanced forms, and the accumulation of fat in the liver causes inflammation, scarring (known as fibrosis), and serious damage to the liver. It can cause severe liver cirrhosis. Patients are usually diagnosed as the disease progresses, and transplantation is the only option.
“Historically, many primary care and diabetes specialists have felt that treating diabetes already addresses the problem, as the root of the disease is insulin resistance,” Sanial said. I have.
“And this shows that even among obese diabetics, those with advanced fibrosis are dying of liver disease. Treating diabetes is not the end of the job,” he adds. I did.
Obesity, Diabetes Causes a Hidden Pandemic of Fatty Liver Disease, Health News, ET Health World
Source link Obesity, Diabetes Causes a Hidden Pandemic of Fatty Liver Disease, Health News, ET Health World